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Tryptamine is the indolamine metabolite of the essential amino acid tryptophan. [2] [3] The chemical structure is defined by an indole—a fused benzene and pyrrole ring—and a 2-aminoethyl group at the second carbon (third aromatic atom, the first being the heterocyclic nitrogen). [2] The structure of tryptamine is shared by certain aminergic neuromodulators such as melatonin, serotonin, and bufotenin, as well as psychedelic derivatives such as dimethyltryptamine (DMT), psilocybin, psilocin, and others. [4] [5] [6] Tryptamine has been shown to activate trace amine-associated receptors expressed in mammalian brain. It also controls the activity of the dopaminergic, serotonergic, and glutamatergic systems. [7] [8] Symbiotic bacteria in the human gut convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates GI motility. [3] [9] [10] A number of tryptamine-derived drugs have been developed to treat migraines, and trace amine-associated receptors are being investigated as a potential treatment target for neuropsychiatric disorders. [11] [12] [13]

Dissociatives

2C-E HCL

$20.00$50.00
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Psychedelics

4-AcO-MET Fumarate

$19.50$190.00
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$18.00$315.00
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$10.00$200.00
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Psychedelics

4-ACO-MiPT

$37.00$275.00
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Psychedelics

4-HO-DPT

$37.00$100.00
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Psychedelics

4-HO-EPT Fumarate

$15.00$120.00
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Psychedelics

4-HO-MET Fumarate

$19.50$450.00
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$18.00$315.00
This product has multiple variants. The options may be chosen on the product page
$18.00$315.00
This product has multiple variants. The options may be chosen on the product page

Psychedelics

5-Br-DMT

$27.00$1,200.00
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