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Molly (Pure MDMA) is an empathogenic drug of the phenethylamine and amphetamine classes of drugs. MDMA has become widely known as “ecstasy”, usually referring to its street form, although this term may also include the presence of possible adulterants.

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3,4-Methylenedioxymethamphetamine

PubChem CID: 1615
Structure:
3,4-Methylenedioxymethamphetamine_small.png
3,4-Methylenedioxymethamphetamine_3D_Structure.png
Chemical Safety:
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Irritant
Molecular Formula: C11H15NO2
Synonyms:

MDMA

3,4-methylenedioxymethamphetamine

Ecstasy

Methylenedioxymethamphetamine

42542-10-9

Molecular Weight: 193.24 g/mol
Dates:
  • Modify:2020-01-25
  • Create:2004-09-16

3,4-Methylenedioxymethamphetamine is a ring-substituted amphetamine derivative, structurally related to the hallucinogen mescaline, with entactogenic, neurotoxic, and motor-stimulatory activities. 3,4-methylenedioxymethamphetamine (MDMA) produces an acute, rapid enhancement in both the release of serotonin from and the inhibition of serotonin reuptake by serotonergic nerve endings in the brain. Once within the cell, MDMA depletes stores of tryptophan hydroxylase (TPH) via acute oxidative inactivation; in turn, depleted stores of TPH leave cell terminals open to damage from oxidative stress, possibly a source of MDMA neurotoxicity. This agent also induces norepinephrine, dopamine, and acetylcholine release and can act directly on a number of receptors, including alpha 2-adrenergic and 5-hydroxytryptamine (5-HT) 2A receptors. MDMA may suppress the dyskinesia associated with long-term use of L-dopamine (L-DOPA) without affecting the efficacy of L-DOPA treatment.

3,4-methylenedioxymethamphetamine is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5. It has a role as a neurotoxin. It is a member of amphetamines and a member of benzodioxoles.

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