BUY 3-HO-PCP
It is classified as dissociative anesthetic, as are other drugs in its class, most notably methoxetamine (MXE), phencyclidine (PCP), and 3-MeO-PCE. 3-HO-PCP was initially synthesized in 1978 to study the structure-activity connection of phencyclidine (PCP) derivatives. It was further investigated alongside PCP in the 1980s, where it was revealed to be a -opioid agonist.
However, there has been relatively little research on this area, thus there is a lot of opportunity for motivated researchers. If you choose to utilize this substance for research purposes, it is strongly advised that you employ proper harm reduction techniques when handling research substances.
HOW TO USE 3-HO-PCP POWDER?
Purchase 3-HO-PCP powder of the highest quality. Phencyclidine PCP is available in 0.25gr, 0.50gr, 1gr, 2gr, and 5gr doses. For best shelf life, keep the 3-HO-PCP powder in a dry and cool place. For the longest shelf life, keep it dry and cool. When working with research chemicals, always take the necessary measures in the laboratory, such as washing down surfaces and wearing gloves, a mask, and protective clothes.
DEFINITION 3-HO-PCP
3-Hydroxyphencyclidine is the formal name for 3-HO-PCP. It belongs to the arylcyclohexylamine class, which is connected to phencyclidine.
3-HO-PCP was initially synthesized in 1978 to investigate the structure of phencyclidine derivatives, also known as PCPs.
CHEMISTRY BACKGROUND INFORMATION 3-HO-PCP
Cyclohexane makes up the structure of 3-Hydroxyphencyclidine. It is a saturated ring with six members. It is made up of two rings: a piperidine ring and an aromatic phenyl ring. In the 1980s, it was investigated further along with phencyclidine. It has -opioid agonists, according to researchers.
3-HO-PCP, like other arylcyclohexylamines, including methoxetamine, phencyclidine, and 3-MeO-PCE, is referred to as “dissociative anesthesia,” albeit the extent to which this occurs has been shown to be highly dose-dependent and variable in its research outcomes.
WHERE TO BUY 3-HO-PCP
3-HO-PCP is available for purchase on the Buy Research Chemicals Online website. We sell high-quality 3-FPM, usually in powder form. However, various chemical forms are frequently available, so please contact us to see if we have your chosen substance form in stock. To purchase 3-HO-PCP from us, you must be at least 18 years old.
What is 3-HO-PCP?
3-Hydroxyphencyclidine (also known as 3-HO-PCP) is a novel dissociative drug of the arylcyclohexylamine class that causes significant dissociative, hallucinogenic, and euphoric effects when taken. In addition to its primary function as an NMDA receptor antagonist, it has been revealed to have a significant affinity for the -opioid receptor.
3-HO-PCP was created in 1978 in order to study the structure-activity relationship of phencyclidine (PCP) derivatives. It was investigated further with PCP in the 1980s, and it was revealed to have -opioid agonist action in animal models.
It is known to primarily induce a state referred to as “dissociative anesthesia” like other substances of its class, particularly methoxetamine (MXE), phencyclidine (PCP), and 3-MeO-PCE, though the extent to which this occurs has been reported to be highly dose-dependent and variable in its effects. It is unclear if the opioid qualities tested in animal models apply to humans, with some preliminary findings indicating that they do not.
Online sellers now almost solely sell 3-HO-PCP as a gray area research chemical. There is very little information available on its pharmacology, metabolism, and toxicity in humans. Because of its sensitive dose-response, potential habit-forming qualities, and uncertain toxicity profile, it is strongly advised that anyone using this substance utilize proper harm reduction measures.
Chemical Properties
3-HO-PCP, often known as 3-hydroxyphencyclidine, is a synthetic dissociative of the arylcyclohexylamine class. The structure of 3-HO-PCP is composed of cyclohexane, a six-membered saturated ring, joined to two extra rings at R1. One of these rings is a piperidine ring, a nitrogenous six-member ring that is bonded at its nitrogen group. The other ring is an aromatic phenyl ring replaced with a hydroxy group at R3.
3-HO-PCP is a structural analog of PCP and the homolog 3-MeO-PCP.
Pharmacological effects
3-HO-PCP, like other arylcyclohexylamine dissociatives, is primarily an NMDA receptor antagonist. The NMDA (N-Methyl-D-Aspartate) receptor, a subtype of glutamate receptor, controls the transmission of electrical signals between neurons in the brain and spinal cord; for the signals to flow, the receptor must be open. Dissociatives disrupt the normal function of NMDA receptors by attaching to and inhibiting them. According to some study, this interruption of neural network activity induces network disintegration through hyperconnectivity across the brain. This creates an increase in noise (random, illogical, and erroneous signals) on the cerebral network, resulting in a loss of normal cognitive and affective processing, psychomotor functioning, and anesthesia. This is frequently found in persons with psychosis or in healthy participants who have received high-dose IV THC or Ketamine.
Unlike many other dissociatives, 3-HO-PCP has been shown in animal models to exhibit a high affinity as a -opioid receptor agonist. However, it is unknown to what extent this applies to humans.
Some of the most commonly reported effects are:
- Stimulation
- Spontaneous bodily sensations
- Anxiety suppression
- Physical & cognitive euphoria
- Tactile enhancement
Potential Side Effects
- Sedation
- Conceptual thinking
- Déjà vu
- Orgasm suppression
- Ego death
Legality
3-HO-PCP is classified as illegal in:
- United Kingdom
- Switzerland
- Sweden
- Turkey
This list is not exhaustive, so do your own research into the legal status in your country before ordering!
How to Buy 3-HO-PCP
You can buy 3-HO-PCP and other dissociatives like 3-HO-PCE, 3-MeO-PCP, and DCK here at Chemical-Vendor. All of our chemicals are third party lab tested.
All of our chemicals are strictly for research and analytical purposes only and not for human consumption.
Product Specifications:
Product Name: 3-HO-PCP hydrochloride
Other Name(s): 3-hydroxyphencyclidine hydrochloride
IUPAC Name: 1-[1-(3-hydroxyphenyl)cyclohexyl]-piperidine hydrochloride
CAS: 79787-43-2
Molar Mass: 295.9 g/mol
Disclaimer | Our 3-HO-PCP Powder is strictly for laboratory use only and is not approved for human consumption. Any mention of dosage/feeding to humans or animals or anything consumption related is not acceptable. |
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